Politics of the Social Web

Following and in some cases consulting/helping in US elections. The impact on the healthcare business and planning is huge. Thought this map of social sites by political affiliation was fascinating.

http://www.facebook.com/photo.php?fbid=280462138740798&set=a.280462132074132.67431.255300841256928&type=1&theater

West Nile outbreak now 2nd worst on record

The Centers for Disease Control and Prevention said 4,531 cases have been reported this year, the highest number since the record outbreak of 2003, when 9,862 cases were reported.
http://af.reuters.com/article/commoditiesNews/idAFL1E8LHDA120121017

Life Technologies Acquires Compendia Bioscience

With all those now insured (again the idea with ACA is to cover people like the 40million who were not instead of saying hey if you get sick go to ER). New merging of informatics and MDx profiles = SCREENING and will be a huge market based on the numbers and one that will SAVE lives and money. Nice move by Life... http://ir.lifetechnologies.com/releasedetail.cfm?ReleaseID=711813

Redefining Medicine With Apps and iPads - The Digital Doctor


The history of medicine is defined by advances born of bioscience. But never before has it been driven to this degree by digital technology.
The proliferation of gadgets, apps and Web-based information has given clinicians — especially young ones like Dr. Rajkomar, who is 28 — a black bag of new tools: new ways to diagnose symptoms and treat patients, to obtain and share information, to think about what it means to be both a doctor and a patient.


Redefining Medicine With Apps and iPads - The Digital Doctor - NYTimes.com

Fungal meningitis cases rise

Centers for Disease Control: Number of confirmed US fungal meningitis cases rises to 47 in 7 states; no new deaths - @Reuters

The First Personalized Medical Treatment for Cancer?

The first use in a patient of a new discovery: how to keep ordinary and cancerous cells alive indefinitely in the lab. The discovery allows doctors to grow "mini tumors" from each patient's cancer in a lab dish, then test various drugs or combinations on them to see which works best. It takes only a few cells from a biopsy and less than two weeks to do, with materials and methods common in most hospitals.

http://www.usatoday.com/news/nation/story/2012/09/26/bizarre-tumor-case-may-lead-to-custom-cancer-care/57846120/1

Here's What Obamacare Does

Until 2014, we will be the only industrialized nation in the world without a comprehensive national health insurance plan. Even then, we will still have a way to go to get us universal care. But before the ACA passed, more than 40 million people had no health insurance and no access to coverage. When it’s fully implemented, that number will be down to around 8 million. Best explanation we've seen.  
Here's What Obamacare Does; Sell it With All Your Might (The PCTC Blog )

Study points to health problems with genetically modified foods


The study, which appeared Wednesday in the journal Food and Chemical Toxicology, was embraced by opponents of genetically altered foods, including backers of Proposition 37, which if approved by California voters in November would require most foods with genetically modified ingredients to bear a label. But the report was sharply criticized by geneticists, who cited its small size and other methodological problems. So will the debate continue? Want to spray pesticides or modify genes?  Which is worse or can we avoid both and still have a decent harvest... that's the challenge.. And how will Monsanto's stock price be impacted?  hmmmm. We all can agree don't wanna a be a lab rat ;(

Study points to health problems with genetically modified foods - Los Angeles Times

Launching a new war on cancer


he cancer center calls the program "an unprecedented effort to dramatically accelerate the pace of converting scientific discoveries into clinical advances that reduce cancer deaths."

Launching a new war on cancer - CNN.com

Analysis of Direct-To-Consumer genomic testing familial data

An initial analysis benchmark in the context of a whole family, using single nucleotide polymorphism (SNP) data. Five blood-related DTC SNP chip data tests were analyzed in conjunction with one whole exome sequence. Report findings related to genomic similarity between individuals, genetic risks and an overall assessment of data quality; thus providing an evaluation of the current potential of public domain analysis tools for personal genomics.

Low budget analysis of Direct-To-Consumer genomic testing familial data | F1000 Research

Cancer now No. 1 killer of U.S. Hispanics - CNN.com

Screening in new ACA = ObamaCare should help fight that:

The research indicates that cancer deaths can be prevented and lives saved among Hispanics if we increase use of proven cancer screening tests; make the hepatitis B and human papilloma virus (HPV) vaccine more widely available; and reduce tobacco use, alcohol consumption and obesity rates. Indeed, this message could be life-saving for all Americans.

Cancer now No. 1 killer of U.S. Hispanics - CNN.com

Superbug kills 7th person at Md. NIH hospital

He was the 19th patient at the hospital to contract an antibiotic-resistant strain of KPC, or Klebsiella pneumoniae. The outbreak stemmed from a single patient carrying the superbug who arrived at the hospital last summer.

Superbug kills 7th person at Md. NIH hospital - Yahoo! News

West Nile cases in U.S. up nearly a third in latest week: CDC - Yahoo! News

So far this year, 2,636 cases have been reported to federal health officials, up from 1,993 the previous week, the Centers for Disease Control and Prevention said in its weekly update of outbreak data. A total of 118 people have died from the disease, compared with 87 reported one week ago. In the late 90's some us where at AMP meetings discussing this future threat, well hear it is and full bore. Please use Mosquito repellent with DEET and get rid of all standing water.

West Nile cases in U.S. up nearly a third in latest week: CDC - Yahoo! News

Nature ENCODE for iPad on the iTunes App Store

The Nature ENCODE app for the iPad brings together the results of the ENCODE project, presented in 30 papers published simultaneously in Nature, Genome Research and Genome Biology. And it's Free!

Nature ENCODE for iPad on the iTunes App Store

For a Lung Cancer, Drug Treatment May Be Within Reach thanks to Genomics

The work became feasible only in the past few years because of enormous advances in DNA sequencing that allow researchers to scan all the DNA in a cell instead of looking at its 21,000 genes one at a time. The result has been a new comprehension of cancer as a genetic disease, defined by DNA alterations that drive a cancer cell’s growth, instead of a disease of a particular tissue or organ, like a breast, the prostate or a lung.

For a Lung Cancer, Drug Treatment May Be Within Reach - NYTimes.com

Ebola virus spreads in eastern Congo


Around 170 people are currently under surveillance after they came into contact with infected patients. Ebola was first discovered in Congo in 1976 and has no cure. The disease causes severe internal bleeding and is fatal in 40 percent to 90 percent of cases.


Ebola virus spreads in eastern Congo - Yahoo! News

Far From ‘Junk,’ DNA Dark Matter Proves Crucial to Health - NYTimes.com

Article says: The discovery, considered a major medical and scientific breakthrough, has enormous implications for human health because many complex diseases appear to be caused by tiny changes in hundreds of gene switches.

Far From ‘Junk,’ DNA Dark Matter Proves Crucial to Health - NYTimes.com

www.milkeninstitute.org/publications/review/2012_7/12-21MR55.pdf


Sixty years after antibiotics were first routinely used
to treat infectious diseases, biological resistance to
these remarkable defenders against micro-organisms
is widespread.  

As my last name is Fleming (penicillin) ... its kinda personal to me!


www.milkeninstitute.org/publications/review/2012_7/12-21MR55.pdf

New: Validated Risk Predictors for Progression to Oral Cancer - Loss of Heterozygosity (LOH)

Study provides the first validated molecular models for use in differentiating low-grade oral dysplasia at low-risk for progression from those with greater risk,

Loss of Heterozygosity (LOH) Profiles—Validated Risk Predictors for Progression to Oral Cancer

Researchers uncover new genetic clues to why most bone marrow transplant patients develop graft-versus-host disease


Researchers found that if a patient and donor have different SNPs, the patient was at increased risk of GVHD or a lower chance of disease-free survival. The scientists surmised that genes located near these SNPs must be involved in that process.
“The question I wanted to ask with this study is whether there could be genes we don’t know about that are located close to the major histocompatibility complex that could be influencing GVHD risk,” said Petersdorf, a member of the Hutchinson Center’s Clinical Research Division. “Now that we know what to test for we can begin screening for the presence of the SNPs in patients and donors and select the optimal donor whose SNP profile will benefit the patient the most.”


Researchers uncover new genetic clues to why most bone marrow transplant patients develop graft-versus-host disease

SINGAPORE SCIENTISTS FIND GENES ASSOCIATED WITH GLAUCOMA, A MAJOR CAUSE OF EYE BLINDNESS


This provides further evidence that genetic factors play a role in development of PACG,” said Prof Aung. “It is a major achievement for our Singapore team leading the largest international consortium of doctors and scientists involved in glaucoma research. The results may lead to new insights into disease understanding and open the possibility of novel treatments in the future as well as the potential of early identification of people at risk of the disease.”

SINGAPORE SCIENTISTS FIND GENES ASSOCIATED WITH GLAUCOMA, A MAJOR CAUSE OF EYE BLINDNESS

J. Craig Venter’s Corporate Strategy? The Scientific Method - NYTimes.com

At Synthetic Genomics, he wants to create living creatures — bacteria, algae or even plants — that are designed from the DNA up to carry out industrial tasks and displace the fuels and chemicals that are now made from fossil fuels.  As a fellow sailor in the waters of SD you know he knows how to tact into the wind too!

J. Craig Venter’s Corporate Strategy? The Scientific Method - NYTimes.com

Cancer Diagnostics – New Ways of Looking at Cancer Progression and Treatment | Biocompare.com

As cancer drugs and other therapeutics become more targeted, which makes them more effective and helps minimize side-effects, it becomes even more crucial to use the right one. New ways to help with that selection ...

Cancer Diagnostics – New Ways of Looking at Cancer Progression and Treatment | Biocompare.com

Scientists find new compound with anti-cancer properties - South India - Kerala - ibnlive


The scientists at the Rajiv Gandhi Centre for Biotechnology (RGCB) along with the scientists at the Mayo Clinic, have found that the compound Plumbagin from common ‘koduveli’ plants (Plumbago species) has enough anti-cancer properties to be developed into an effective anti-cancer drug. They found that plumbagin cuts off new blood vessels to cancer cells, affecting its growth and proliferation.  This (I think) is another reflection on the historic work of Dr. David Baltimore and angiogenesis.


The findings have been published in the latest issue of the International Journal of Cancer.

Scientists find new compound with anti-cancer properties - South India - Kerala - ibnlive

Empirical antibacterial treatment of infection with Chlamydophila pneumoniae in Multiple Sclerosis

Link of Chlamydia to Multiple Sclerosis

http://www.davidwheldon.co.uk/ms-treatment1.html

How a virus might make you diabetic later in life

New research published in BioMed Central's open access journal Immunity and Ageing shows that CMV infection is a significant risk factor for the type 2 diabetes in the elderly.

How a virus might make you diabetic later in life

Atrial Fibrillation and Dementia: An Association Beyond Stroke?

Recent studies have suggested that Atrial Fibrillation itself is a risk factor for dementia even in the absence of clinical stroke.

Atrial Fibrillation and Dementia: An Association Beyond Stroke?

New all in one HIV pill (4 meds in 1) approved

FDA approved Gilead Sciences' Stribild as a once-a-day treatment to control the virus that causes AIDS.
News from The Associated Press

Doctors envision the day when every patient will have therapy precisely matched to the genetic bull’s-eyes of their own cancers

We are not there yet and today's targeted therapies cost a lot of $

http://www.thedailybeast.com/newsweek/2012/08/26/the-cancer-breakthroughs-that-cost-too-much-and-do-too-little.html

With Rise of Gene Sequencing, Ethical Puzzles - NYTimes.com

In laboratories around the world, genetic researchers using tools that are ever more sophisticated to peer into the DNA of cells are increasingly finding things they were not looking for, including information that could make a big difference to an anonymous donor.

With Rise of Gene Sequencing, Ethical Puzzles - NYTimes.com

Human Evolution

More sophisticated wiring, not just a bigger brain, helped humans evolve beyond chimps http://t.co/Zw8oxzk4

What's all this about abortion and rape?

Yikes, I live in a country where a delusional idiot can get elected?

http://www.theonion.com/articles/poll-reveals-you-live-in-country-where-mentally-il,29274/

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