"Until now, rat geneticists lacked a viable technique for 'knocking out,' or mutating, specific genes to understand their function," said Howard Jacob, Ph.D. Director of the Human and Molecular Genetics Center at the Medical College of Wisconsin. "This study demonstrates that ZFN technology bypasses the current need to conduct cumbersome experiments involving nuclear transfer (cloning) or embryonic stem cells and allows rapid creation of new animal models."
David Cox, a Ph.D. student in computer science at NC State, devised the "symbolic scatter plot" tool to provide a visual representation of a DNA sequence. Cox explains, "The human visual system is more adept at identifying patterns, and differentiating between patterns, than existing computer programs such as those that try to identify repetitions of DNA sequences." In other words, the naked eye sees patterns better than computers can.
Shares in Qiagen rose more than 5 percent on Friday as traders cited market talk that French drug specialist Sanofi-Aventis was considering a bid for the German Biotech. "I've heard talk of a bid of 14.50 euros per share for Qiagen," a Frankfurt-based trader says. A spokesman at Sanofi-Aventis said the company does not comment on market rumours.
U.S. health officials are seeing a surprisingly high number of cases of ordinary, seasonal flu at a time when the flu season typically peters out.
About half of people recently testing positive for the flu have the new swine flu virus, Dr. Daniel Jernigan of the Centers for Disease Control and Prevention in Atlanta said Friday.
"The H1N1 virus is not going away," Jernigan said. The virus "appears to be expanding throughout the United States" and poses "an ongoing public health threat," he said.
Swine flu continues to affect more younger people — those ages 5 to 24 — and CDC is still seeing relatively few cases in older people
In the United States, there are now more than 4,700 probable and confirmed cases of swine flu, and 173 hospitalizations and four deaths, Jernigan said. The tally doesn't include a fifth death that Texas officials said Friday was due to swine flu.
Experts say develop eggs using stem cells from mice
(technology available now from Sigma-Aldrich, CompoZr ZFN)
See #4 Curing HIV in Germany
Top 10 Scientific Breakthroughs of 2008 Wired Science from Wired.com: "
Princeton University - Team finds breast cancer gene linked to disease spread
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