Statins may promote oligodendrocyte lineage commitment by parenchymal glial progenitor cells; this might reduce the available progenitor pool, and hence degrade the long-term regenerative competence of the adult white matter.
Wiley InterScience :: JOURNALS :: Glia
GEN News Highlights
Statins affect glial progenitor cells, which are important to brain health as we age, according to a group of scientists. These cells are similar to stem cells and can become either astrocytes or oligodendrocytes. The researchers found, however, that statins caused the glial progenitor cells to turn into only oligodendrocytes.
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