"The plants are more relaxed," says Metzlaff. "They can lean back and just do what they have to do."
Metzlaff's method can be very specifically targeted to a plant of choice, using parts of the PARP genetic sequence that do not exist in other species. This tight control should allay fears from the anti-GM lobby that the RNA molecule could spread and harm other species in the area.
Science: The GM crop that will sow less bitterness - Telegraph
Glow-in-dark cats may enlighten humans - Science - Specials - smh.com.au\
Oh, I gotta get me one of these!
As Drug Industry Struggles, Chemists Face Layoff Wave - WSJ.com
Blood Test to Detect Lung Cancer Being Eyed - Forbes.com
Genes Yield More Clues to Schizophrenia - Forbes.com
BioBOOM Op/Ed: Ok new pre-employment screen !
More intriguing, the work marks an important step in studying how our environment - food, stress, pollution - interacts with genes to help determine why some people get sick and others do not.
"What we have is a bag of gold nuggets," lead researcher Dr. Randy Jirtle said about the collection of "imprinted" genes. The team's findings were published online Friday by the journal Genome Research.
Next comes work to prove exactly what role these genes play. "Some will be real gold and some will be fool's gold," Jirtle added.
newsobserver.com Duke scientists identify 'silenced genes'
Rite Aid Stores in West Selling a Paternity Test Kit - New York Times
U.S. Senators have access to a wide range of insurance options through the Federal Employees Health Benefits Program. Congress has its own “attending physician” — actually, a team of 5 doctors and 14 nurses who work in the Capitol and nearby Congressional office buildings. Lawmakers can fill prescriptions at a small pharmacy in the Capitol. For more serious problems, they can use nearby military hospitals.
Just Off Insular Senate Floor, Life of the Uninsured Intrudes - New York Times
Man Who Helped Start Stem Cell War May End It - New York Times
On Wisconsin ..On Wisconsin...
. . . . FORWARD
Scientists Bypass Need for Embryo to Get Stem Cells - New York Times
Cannabis Compound May Stop Metastatic Breast Cancer - Yahoo! News
Smok'em if ya gott'em but then again the lung cancer might get ya instead
"It's an exciting step forward -- people have been trying to get traction on this big clinical problem for about 40 years, and this is a big crack in the door," said lead researcher Thea Tlsty, a professor of pathology at the University of California, San Francisco.
Cell Insights May Predict Breast Cancer's Spread - Yahoo! News
Report Urges Regulation of Genetic Tests - Forbes.com
Monsanto is developing genetically modified plants that use RNA interference to kill the insects that eat them
Technology Review: Crops That Shut Down Pests' Genes
Sigma-Aldrich and Oxford BioMedica Win Key Ruling in Open Biosystems Patent Infringement Dispute: Financial News - Yahoo! Finance
On October 23rd, 2007 a cool indie movie, RAPID EYE MOVEMENT, will be officially released and available on DVD. This indie thriller is 90 minutes of fast paced excitement! It stars Kansas Carradine in her feature debut, (daughter of KILL BILL 1 and KILL BILL 2's David Carradine), along with Federic Vial, who is the star of the BMW Motorcycle Films. Just in time for Halloween, this film has received 3.5 out of 4 stars on HorrorYearBook.com. Dr. Royce Clemens is quoting as saying, “As it stands, RAPID EYE MOVEMENT is a very impressive work that shows great promise. And in the land of the timid, I was blown away by the film’s insistence upon itself and the Mad-Prophet zeal of Tuckman himself.”
The film was shot on a shoe string budget with the heart and soul of true indie filmmaking and will keep you entertained to the very twisted ending.
You can check out the trailer at:
and buy your own copy at:
If you can, please forward this to your friends to help with our grass roots effort to support indie films. Thank you and enjoy the show!
I am creating artificial life, declares US gene pioneer Science The Guardian
A computer program developed at MIT could vastly improve the design of antibody drugs. The software identified improvements in the anticancer drug cetuximab that increased its binding affinity by a factor of 10 in subsequent laboratory tests--a change that could lead to lower drug dosages and increased drug efficacy.
Technology Review: Computers Boost Antibody-Based Drugs
MicroRNAs may be key to HIV's ability to hide, evade drugs, Jefferson scientists find
Official University of Alberta DCA Site
Canadian Food Inspection Agency - Avian Influenza - Saskatchewan (2007) - Public Notice - MOVEMENT RESTRICTIONS IN PLACE TO PREVENT THE SPREAD OF AVIAN INFLUENZA IN SASKATCHEWAN
Technology Review: Natural Products Made in a Test Tube
DNA unraveled - The Boston Globe
In the coming decade, pharmaceutical products--especially cancer drugs--will be created in tandem with diagnostic tests that tell doctors which patients are likely to benefit. Right now, physicians often feel they're flying blind. Each patient arrives at the hospital with a unique genetic makeup, which affects whether a prescribed drug will kill tumor cells, cause devastating side effects, or possibly do nothing at all. If a new generation of gene tests can help predict these different outcomes, patients will be spared expensive and unhelpful ordeals. The pool of target patients for many medications will also shrink. But if doctors are confident a drug will help somebody, they'll prescribe it aggressively, and insurers will be more likely to foot the bill.
A Dream Team Of Drugs And Diagnosis? Business Week.
Senate OKs FDA drug safety bill - washingtonpost.com
Genome Area Linked to Rheumatoid Arthritis - washingtonpost.com
In addition, the National Cancer Institute is helping companies find a way to collaborate in drug testing without worrying about intellectual-property issues. The medical journal the Oncologist is encouraging the publication of failed medical trials in order to bring the ideas behind these trials -- which otherwise would never see the light of day -- to a broader audience. And Mr. Goldstein's father, Alfred, with help from the family's other son, Mark, also developed a venture that aims to improve idea-sharing: Through "Project Hope," named for his late wife, Alfred Goldstein guarantees certain funding for specific projects and requires the researchers share results with each other on a regular basis.
The Gotham Prize is a particularly ambitious project that is attracting attention. The foundation of the Ira Sohn Investment Research Conference, which runs the conference as a benefit to raise money for cancer, will fund an additional $250,000 prize for the best pediatric-cancer idea submitted to the Gotham site. Ephraim Gildor, founder of Axiom Investment Advisors, is also providing financial support for the prize.
Will Sharing Ideas Advance Cancer Research? - WSJ.com
Some of the highlights from just the past year:
Last August, a U.S. team announced the first-ever gene test aimed at pinpointing which patients with early stage lung cancer will benefit from post-operative chemotherapy, and which can be spared the arduous treatment.
That same month, Canadian researchers reported on a new model to speed the identification of mutations linked to a silent killer, ovarian cancer. Spotting those genes could pinpoint women at risk.
A $100 million U.S. project called the Cancer Genome Atlas announced its first major achievement in September -- the mapping of genomes for breast and colon cancer. Scientists say they were able to identify 100 mutations thought responsible for each of those malignancies.
In March, British scientists reported that they had pinpointed 100 mutated genes that help drive more than 210 different cancer types. "This set of genes is known to regulate key functions in virtually all cell processes of growth, differentiation," researcher Andrew Futreal, of the Wellcome Trust Sanger Institute in Cambridge, said at the time.
And, in April, a team at Duke University said it had found genes that encourage breast cancer's spread to the lungs, as well as mutations that hamper chemotherapy's therapeutic effects.
It all looks very promising. But Lichtenfeld said that every DNA discovery has its downside, too.
"The more that we learn, the more complex it is going to get," he said.
Genetics Hold Promise, Challenges for Cancer Care - Yahoo! News
Wine grape genome decoded, flavour genes found - Yahoo! News
Study Finds Virus Contributes to Obesity - washingtonpost.com
That first cell of synthetic life - made from the basic chemicals in DNA - may not seem like much to non-scientists. For one thing, you'll have to look in a microscope to see it.
"Creating protocells has the potential to shed new light on our place in the universe," Bedau said. "This will remove one of the few fundamental mysteries about creation in the universe and our role."
And several scientists believe man-made life forms will one day offer the potential for solving a variety of problems, from fighting diseases to locking up greenhouse gases to eating toxic waste.
Bedau figures there are three major hurdles to creating synthetic life:
- A container, or membrane, for the cell to keep bad molecules out, allow good ones, and the ability to multiply.
- A genetic system that controls the functions of the cell, enabling it to reproduce and mutate in response to environmental changes.
- A metabolism that extracts raw materials from the environment as food and then changes it into energy.
Artificial life likely in 3 to 10 years from the AP health wire
Inflammation, Angiogenesis And Breast Cancer Linked In Chain Of Events
Amgen cutting costs as key anemia drug sales fall News Market News Reuters
Patient in Experimental Gene Therapy Study Dies, F.D.A. Says - New York Times
Key to a long life -- less insulin in the brain Health Reuters
The scientists engineered an enzyme which attacks the DNA of the HIV virus and cuts it out of the infected cell, according to the study published in Science magazine.
Potential cure for HIV discovered - Forbes.com
Therapies based on RNA interference have become the next great hope for medicine, and a large number are either in or about to start early clinical trials in humans.
Research brings hope of curing brain disease Special reports Guardian Unlimited
As Breeders Test DNA, Dogs Become Guinea Pigs - New York Times
12 Gene Tests That Could Change Your Life - Forbes.com
Gene Therapy Used to Cure Mice Blindness - New York Times
Wake-up call to genes may lead to cure for baldness - Independent Online Edition > Health Medical
Thomas Pento and Roger Harrison helped develop a fusion protein that keeps some types of cancer cells from ingesting a vital protein called methionine. The fusion protein doesn't affect normal cells because, unlike cancer cells, they can be healthy without that protein
Okla. Professors Develop Cancer Protein - washingtonpost.com
The cells have shown promise in lab animal treatment of diabetes, heart disease and wounds
Elusive 'ambulance' cells are created - USATODAY.com
New Hampshire Law Banning Commercial Use of Prescription Information Declared Unconstitutional: Financial News - Yahoo! Finance
Cancer Biomarkers Could Help Guide Treatment - Forbes.com
Gene discovery raises hope of treatment for memory loss Special reports Guardian Unlimited
Politics called threat to CDC ajc.com: "vaccinations.'"
Tuberculosis in South Africa - A Global System in Crisis - Health - News - New York Times
The cancer atlas will catalog mutations in primary tumors—those solid masses in lung, breast, prostate and other tissues. But what kills an estimated 90 percent of cancer patients is not the primary tumor (you can live without a prostate). It is metastases. These are malignant cells that spread to a vital organ like the brain. "What matters for survival is not the primary tumor but the rare cells—1 in 50,000—in it that give rise to metastases," says Miklos. Identifying all the mutations in a tumor is overkill, especially since the atlas will not zero in on mutations that underlie metastasis.
$1.5 Billion Doesn’t Guarantee Good Science - Newsweek Technology - MSNBC.com
Check out the article....
Technology Review: Special Reports: 10 Emerging Technologies
"Instead of being at the end of discovery, it means we're in the earliest stages," said Venter, chairman of the J. Craig Venter Institute, a nonprofit gene research center. "That is a pretty stunning view."
Seas Yield Surprising Catch of Unknown Genes - washingtonpost.com
BioBOOM Op/Ed: As our sea going hero of the "omics" era continues his ability to discover....How would you like to be in a business model that will last some time?
We read from this that those companies supplying tools, instruments, infomatics and reagents to support the laboratory based "mining" effort of genes and proteins are in for a continued long term ride it seems. Way to go Craig!
Affymetrix Shares Up On Legal Victory - Forbes.com
It is only within the past ten years that a new array of high-speed genetic tools has made network maps possible, by allowing researchers to look at thousands of genes or proteins at once and measuring how they interact. Then researchers can go back to cells or animals to test whether the predictions hold true.
Friendster for Proteins - Forbes.com
Scientists Discover 'Natural Barrier' to HIV - Yahoo! News
6 Get Grants From U.S. to Support Bio-Refineries - New York Times
The researchers believe the membranes could be used like sieves to filter light gases through an atomic mesh or to make miniature electro-mechanical switches. They could also be used as non-obscuring support for electron microscopy to study molecules, allowing for the quick analysis of atomic structures of bio-active molecules in medical research
New ultra-thin technology developed The Australian
AIDS virus weakness detected - Yahoo! News
Lab disaster may lead to new cancer drug | Reuters.com
BBC NEWS | Health | Human metabolism recreated in lab
Scientists Develop Gene-Activating Technique - Forbes.com
Rumors Fly About Bristol, Lifting Stock - New York Times
Drug developer MDS Inc. said Monday it is buying bioanalytical measurement systems maker Molecular Devices Corp. for $615 million in cash. Under terms of the deal, MDS will pay $35.50 per share for all outstanding shares of Molecular Devices. The offer represents a 48.7 percent premium over Molecular Devices' closing price of $23.88 on Friday. The total price includes $585 million to buy outstanding shares plus $30 million for outstanding stock options
MDS Buying Molecular Devices for $615M
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