Virus Uses Tiny RNA to Evade the Immune System

When scientists found that RNA interference appeared to be a basic and widespread gene regulatory mechanism, “it became clear that such a fundamental pathway could of course be pirated by a virus,” said postdoctoral fellow Adam Grundhoff, co-first author of the paper. Viruses can use the host RNA inference machinery, which is often speculated to have evolved as an antiviral mechanism, to generate small RNAs that serve their own purposes — the latest chapter in the long cat-and-mouse game known to virologists as host-virus coevolution,” the researchers conclude in their Nature article.


HHMI News: Virus Uses Tiny RNA to Evade the Immune System

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