Trio of Leukemias Shares a Single Mutation

Three leukemias that affect as many as 100,000 people in the United States are all caused by acquired mutations that alter a specific enzyme controlling blood cell proliferation, according to new studies by Howard Hughes Medical Institute (HHMI) researchers. This means they may be able to devise a targeted therapy, just as they have done for chronic myelogenous leukemia (CML), which is presently treated with Gleevec. The three leukemias that share a common genetic cause are polycythemia vera (PV), essential thrombocythemia (ET) and myeloid metaplasia with myelofibrosis (MMM).

HHMI News: Trio of Leukemias Shares a Single Mutation

BioBOOM Op/Ed: More interesting to us is the comment at the close of the article that says the internet-based clinical protocol is the first time that a research group has used it as a protocol for collecting blood samples to identify the cause of a disease.

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